SMIF’s cryo-TEM instrumental in development of coronavirus vaccine

Researchers at Duke are hard at work in the development of a novel vaccine to fight the coronavirus. The cryo-transmission electron microscope housed at Duke’s Shared Materials Instrumentation Facility (SMIF) is playing a major role in this work. This microscope helps scientists determine the structure of proteins in the virus to help guide vaccine design. To learn more, see the press release here.

Cryogenic Scanning Electron Microscopy (CryoSEM) Short Course

NC State’s Analytical Instrumentation Facility (AIF) offers a hands-on short course on Cryogenic Scanning Electron Microscopy (SEM) on a routine basis.  There is a 1.5 hr lecture on CryoSEM theory, application, and sample preparation. Each student will get hands-on time (90 minute or more per student) for preparing CryoSEM samples and running the AIF JEOL JSM-7600 SEM.  The goal of the course is to provide students a basic understanding of both theory and practice.  To ensure each student receives maximum hands-on time, the course will be limited to 4 participants.

For more details and to register, please contact Chuanzhen Zhou at Registration costs: $50 for academic, government, and non-profit participants; $350 for industry participants. RTNN is able to offset costs associated with registration and travel to a limited number of participants who demonstrate need. To apply for support, please visit the RTNN support page.

CryoSEM Now Available to RTNN Users

The Analytical Instrumentation Facility (AIF) at NC State recently added the CryoSEM JEOL JSM-7600 to its characterization repertoire. This system can be used to evaluate hydrated, beam sensitive, volatile and low melting point specimens that are normally difficult to image in traditional SEM. The image displayed here shows the microstructure of a fibrin-thrombin hydrogel in its hydrated state. For more information, please visit the AIF website or contact Chuanzhen Zhou at her email