RTNN Facilities Support COVID-19 Research

Protochips uses the NC State Nanofabrication Facility and Analytical Instrumentation Facility to manufacture and analyze in situ TEM holders and sample supports. One of Protochips’s customers, the McLellan Lab at the University of Texas, determined the 3D structure of the SARS-CoV-2 spike protein, a critical first step towards developing a vaccine.This reconstruction is widely used, including on the homepage of the CDC. A recent Raleigh Magazine article highlighted this work.

In collaboration with other researchers, Alexander Kabanov’s group in UNC’s Eshelman School of Pharmacy is developing mechanisms to deliver anti-CoV drugs and therapeutic agents directly to the respiratory track. Kabanov’s team uses instruments in the Chapel Hill and Nanofabrication Laboratory to characterize their work.

In addition, researchers at Duke are hard at work in the development of a novel vaccine to fight the coronavirus. The cryo-transmission electron microscope housed at Duke’s Shared Materials Instrumentation Facility (SMIF) is playing a major role in this work. This microscope helps scientists determine the structure of proteins in the virus to help guide vaccine design. To learn more, see the press release here.

SMIF’s cryo-TEM instrumental in development of coronavirus vaccine

Researchers at Duke are hard at work in the development of a novel vaccine to fight the coronavirus. The cryo-transmission electron microscope housed at Duke’s Shared Materials Instrumentation Facility (SMIF) is playing a major role in this work. This microscope helps scientists determine the structure of proteins in the virus to help guide vaccine design. To learn more, see the press release here.

Transmission Electron Microscopy Short Course

NC State’s Analytical Instrumentation Facility (AIF) is giving a hands-on short course on transmission electron microscopy (TEM) and related techniques, which are very powerful to understand the morphology, structure, defects, crystal orientation and phase information of materials, as well as the chemical distribution down to atomic resolution. It is meant for new TEM users with an interdisciplinary background and/or those interested in learning advanced characterization techniques. The course will include 1.5 hours of theory component and the rest of the day will be in laboratories.

This introductory course will cover the following topics:

  1. Basic principles of TEM
  2. Basic diffraction and imaging
  3. Introduction of advanced characterization techniques

After completion of this course, the attendee will be able to gain theory and practical knowledge on how to do basic imaging and diffraction within TEM, what information the advanced TEM techniques can provide, as well as how to design their own experiments for their projects.

Registration costs: $50 for academic, government, and non-profit participants; $350 for industry participants.

For more details and to register, please visit the short course website.

NC State’s Analytical Instrumentation Facility (AIF) is giving a hands-on short course on transmission electron microscopy (TEM) and related techniques, which are very powerful to understanding the morphology, structure, defects, crystal orientation, and phase information of materials, as well as the chemical distribution down to atomic resolution. It is meant for new users of the TEM  with interdisciplinary background and/or those interested in learning advanced characterization techniques. The course will include a theory component in the morning (9:00 am to 11:00 am), and the rest of the day will be laboratories.

This introductory course will cover the following topics:

  1. Basic principles of TEM.
  2. Basic diffraction and imaging.
  3. Introduction of advanced characterization techniques.

During this course, the attendee will obtain theoretical and practical knowledge on how to conduct basic imaging and diffraction using TEM, and what information the advanced TEM techniques can provide, as well as how to design their own experiments for their projects.

For more details and to register, please contact Dr. Yang Liu at his email yliu78@ncsu.edu. Registration costs: $50 for academic, government, and non-profit participants; $350 for industry participants.

Transmission Electron Microscopy Short Course

NC State’s Analytical Instrumentation Facility (AIF) is giving a hands-on short course on transmission electron microscopy (TEM) and related techniques, which are very powerful to understanding the morphology, structure, defects, crystal orientation, and phase information of materials, as well as the chemical distribution down to atomic resolution. It is meant for new users of the TEM  with interdisciplinary background and/or those interested in learning advanced characterization techniques. The course will include a theory component in the morning (9:00 am to 11:00 am), and the rest of the day will be laboratories.

This introductory course will cover the following topics:

  1. Basic principles of TEM.
  2. Basic diffraction and imaging.
  3. Introduction of advanced characterization techniques.

During this course, the attendee will obtain theoretical and practical knowledge on how to conduct basic imaging and diffraction using TEM, and what information the advanced TEM techniques can provide, as well as how to design their own experiments for their projects.

For more details and to register, please contact Dr. Yang Liu at his email yliu78@ncsu.edu. Registration costs: $50 for academic, government, and non-profit participants; $350 for industry participants